Monthly Archives: November, 2009
Understanding how epigenetics influences weight
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In human weight loss studies, response to a given restriction of calories does not produce the same level of weight loss in every subject. Though genetic factors clearly have some role per monozygotic twin and gene manipulation studies, even then there are differences. Epigenetics is a likely candidate to explain these observations.
So, Bouchard et [...]
An epigenetic mechanism for peripheral insulin resistance
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PGC-1alpha is my favorite gene/protein to study, as it is essential for mitochondrial regulation, influential on many diseases and ageing. I also am fascinated by the relatively new field of epigenetics and its relation to nutrition and health. So you can understand my geeky giddiness when I found that a study by Barrès et al. (1) shows [...]
Eating speed and calorie control: Weight of the evidence
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Recently, a paper by Kokkinos et al. (1) was published on an experiment finding different postprandial Peptide YY and Glucagon-Like Peptide-1 concentration responses with varying eating speed. This immediately prompted such media headlines as: “Eating Slowly May Help Weight Control,” “Cut Calories by Eating Slowly,” “Eating Slowly Can Help with Weight Loss,” and “Eating Quickly [...]
