Author Archives: Colby Vorland

The complex lipidome quantified

There are thousands of lipid species in our bodies that represent 6 categories, but we only usually hear about the subcategories of cholesterol and triglycerides.  We don’t yet understand how they are all altered in response to various nutrients, dietary … Continue reading

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Posted in Lipidomics, Lipids, Metabolomics, Nutrigenomics | View Comments

The negative stigma of creatine in the media continues

Earlier this week, I caught an article in the New York Times covering a rare occurrence: 24 members of a high school football team in Oregon developed rhabdomyolysis (muscle breakdown) from an intense workout with limited water in very hot temperatures.  Rhabdomyolysis … Continue reading

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Choose foods, not nutrients

Last week, Yoni Freedhoff highlighted a great JAMA editorial by Dariush Mozaffarian and David Ludwig entitled “Dietary Guidelines in the 21st Century-a Time for Food.” (1).  It is a short but smart commentary by 2 researchers who clearly see the … Continue reading

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Posted in Dietary Guidelines, Macronutrients | View Comments

Muscle memory: it’s in the myonuclei

Previous studies have indicated that after resistance training and subsequent refrainment for varying time periods, we regain muscle force and mass more quickly in response to training compared to how long it took intially.  In fact, after discontinuing training for … Continue reading

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Posted in Muscle | View Comments

Ageing per se increases susceptibility to lipid induced insulin resistance in rats

I am constantly on the lookout for studies on how biochemical mechanisms shift with age, the significance of these changes and how nutrition and lifestyle interact with them to potentially affect health.  Ageing itself is clearly an immensely complex process, and teasing … Continue reading

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Posted in Ageing, Dietary Restriction, Insulin Resistance, Pathologies | View Comments

Does nutrition need a new research paradigm?

When you consider how highly complex food systems interact with highly complex human systems, it is a bit overwhelming.  Then consider the thousands of different food species, nutrients, dietary patterns and combinations, how these interact with differing activities and other … Continue reading

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Posted in Nutrigenomics, Nutritional Science | View Comments

ADA and corporate sponsorship part 2

Last week I ranted about the ADA and its corporate sponsors after hearing about the latest sponsorship by Hershey. Fooducate also commented about this, took the initiative to contact the ADA, and posted some of the statements along with some great comments. … Continue reading

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Posted in ADA (American Dietetic Association) | View Comments

A note on the ADA, corporate sponsorship, and PepsiGate

Last week, the American Dietetic Association announced a new corporate sponsor: The Hershey Center for Health & Nutrition.  The press release is vague but states that they: “…will collaborate with ADA on consumer and health professional initiatives including an innovative, … Continue reading

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Exploring epigenetic modifications in fatty liver with berberine

Last year, I described a study that found an epigenetic mechanism of peripheral insulin resistance through methylation of the PGC-1alpha promoter.  Recently, Chang et al. explored an epigenetic mechanism in non-alcoholic fatty liver. Fatty liver is closely linked with insulin … Continue reading

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Caffeine in coffee, an inconsistent “fix”

I have often wondered why, when buying coffee from the same establishment on different days, or the same size from different establishments- they do not have an equal effect on my subjective alertness.  It probably has a lot to do … Continue reading

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Posted in Coffee | View Comments