Category Archives: Epigenetics

Last year, I described a study that found an epigenetic mechanism of peripheral insulin resistance through methylation of the PGC-1alpha promoter.  Recently, Chang et al. explored an epigenetic mechanism in non-alcoholic fatty liver. Fatty liver is closely linked with insulin … Continue reading →

In human weight loss studies, response to a given restriction of calories does not produce the same level of weight loss in every subject.  Though genetic factors clearly have some role per monozygotic twin and gene manipulation studies, even then … Continue reading →