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Category Archives: Pathologies
Ageing per se increases susceptibility to lipid induced insulin resistance in rats
I am constantly on the lookout for studies on how biochemical mechanisms shift with age, the significance of these changes and how nutrition and lifestyle interact with them to potentially affect health. Ageing itself is clearly an immensely complex process, and teasing … Continue reading
Posted in Ageing, Dietary Restriction, Insulin Resistance, Pathologies
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How strong is the HDL-cardiovascular disease hypothesis?
A lot of nutritional studies, especially epidemiological, rely on certain biomarkers to assess disease risk. Many of these biomarkers are accepted with little challenge, and thus become very common to examine. Historically, jumping too quickly to conclusions from associations has … Continue reading
Posted in Cardiovascular Disease, Pathologies
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Insulin resistance as a protective mechanism, a paradigm shift?
Oxidative stress has been implicated implicated in insulin resistance, and a new study by Hoehn et al. (1) adds some convincing evidence that one specific radical, superoxide generated in the mitochondria, may be a unifying cause. But the findings suggest … Continue reading
Posted in Insulin Resistance
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